ARCH™ lateral sampling devices enable performance of transbronchial needle aspiration (TBNA) and sampling of peripheral nodules by transbronchial biopsy (TBB). Both of these procedures are complex tasks given the small caliber of the inner spaces of the bronchial diameter.
Bronchoscopy is a minimally invasive procedure that allows exploration of the bronchial tree, as well as diagnostic and therapeutic activities using sophisticated flexible fiber optic equipment.
One of the most important indications for bronchoscopy is lymph node sampling for lung cancer staging, since lymph node involvement has a significant impact on the individual plan for lung cancer therapy. Lung cancer is the leading cause of cancer death for both men and women, with an incidence of 216,000 new cases and 161,000 deaths in the US alone in 2012.
The bronchial lymph nodes are located around the bronchial tree and require unique equipment and skills for the performance of a biopsy via a bronchoscope. At present, a specially designed needle is inserted into the bronchoscope, in a procedure called transbronchial needle aspiration, or TBNA. Alternatively, lymph node sampling can be performed by mediastinoscopy, a surgical procedure carried out under full anesthesia with a significantly higher complication rate.
According to the National Lung Screen Trial (NLST) study, the diagnosis of peripheral solitary pulmonary nodules (SPN) represents a critical unmet need. In most practices sampling is performed with transbronchial biopsy (TBB) or by CT-guided biopsy with success rates around 40%.